Chiari tip I malformasyonlu hastalarda korpus kallozumun morfometrik ölçümlerinin ve uzaysal

Aim. This study aimed to determine the morphometric measurement and spatial orientation of corpus callosum in patients with Chiari type I malformation. Methods. In 28 patients with Chiari type I malformation (14 women and 14 men) and 41 healthy individuals between the ages of 3-65, length and height of corpus callosum as well as the central angle and four angles (A, B, C, D angles) to understand the spatial characteristics of the callosum were measured in T1 or T2 weighted mid-sagittal MR images. Independent-T test was used to determine the statistical differences between the measurements. Moreover Pearson's coefficient of correlation was used to determine the correlations. Results. B and D angles of corpus callosum compared between the groups, had a significant difference (p<0.001). There was no statistical difference between the length and height of corpus callosum, as well as the central angle and other two angles (A and C) for spatial characteristics of the corpus callosum (p>0.05). There was a positive correlation between the age and length of corpus callosum and A angle (r: 0.446 p: 0.043, r: 0.494 p: 0.023, respectively). There was no correlation between gender and morphometric measurements. Conclusion. These results confirm that the spatial orientation of corpus callosum is different from the normal population in cases with Chiari Type I malformation. These results suggest that spatial orientation could be an important factor in studies of the corpus callosum, however, further studies are required with larger sample size.